Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.49 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.49 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | BLVRB | P30043 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12365280 | 0.83 | ALDH1A1 (0.49) | SRD5A2SRD5A1KMORXRATDP2 | |
| SCHEMBL6069049 | 0.76 | SRD5A2 (0.51) | SRD5A2SRD5A1RXRA | |
| SCHEMBL12365039 | 0.75 | TDP2 (0.42) | FOLH1SRD5A2SRD5A1KMOAKR1C3 | |
| SCHEMBL12365042 | 0.75 | TDP2 (0.42) | FOLH1SRD5A2SRD5A1KMORXRA | |
| SCHEMBL6051820 | 0.75 | ACMSD (0.56) | FOLH1KMORXRARXRBALDH1A1 | |
| SCHEMBL12365040 | 0.74 | SRD5A2 (0.58) | SRD5A2SRD5A1KMORXRAALDH1A1 | |
| SCHEMBL27853805 | 0.74 | SERPINE1 (0.51) | FOLH1KMOPTGER1RXRARXRB | |
| SCHEMBL12365294 | 0.74 | SRD5A2 (0.47) | SRD5A2SRD5A1ALDH1A1NR1H4 | |
| Hydrochloric Acid SCHEMBL8442689 | 0.74 | HTR2B (0.51) | — | |
| SCHEMBL12365081 | 0.72 | RARA (0.48) | FOLH1SRD5A2SRD5A1KMOTDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773927-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996004241-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |