Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.48 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8133729 | 0.92 | CYP19A1 (0.47) | CYP19A1MAPK14GPR132ACACBMRGPRX4 | |
| SCHEMBL8807328 | 0.81 | MAPK14 (0.48) | CYP19A1MAPK14GPR132 | |
| SCHEMBL8119481 | 0.78 | MAOB (0.54) | CYP19A1CYP11B1GPR132MRGPRX4 | |
| SCHEMBL8808917 | 0.77 | XDH (0.45) | CYP19A1MAPK14MRGPRX4 | |
| SCHEMBL8809211 | 0.76 | MAOB (0.54) | MRGPRX4 | |
| SCHEMBL21585879 | 0.76 | BRD4 (0.48) | MAPK14CYP11B1GPR132CYP11B2 | |
| SCHEMBL30359958 | 0.76 | BRD4 (0.48) | MAPK14CYP11B1GPR132CYP11B2 | |
| SCHEMBL8119668 | 0.76 | — | — | |
| SCHEMBL8812284 | 0.74 | CYP19A1 (0.41) | CYP19A1MRGPRX4 | |
| SCHEMBL8809208 | 0.74 | MAOB (0.51) | CYP11B1CYP11B2MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805802-A1 | SUBSTITUTED PHENYL COMPOUNDS AS ENDOTHELIN ANTAGONISTS | RHONE-POULENC RORER LIMITED (GB) | 1997-11-12 | — | — | EP | claimed |
| WO-1996022978-A1 | SUBSTITUTED PHENYL COMPOUNDS AS ENDOTHELIN ANTAGONISTS | RHONE POULENC RORER LIMITED (GB) | 1996-08-01 | — | — | WO | claimed |