Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807544 | 0.92 | BCHE (0.48) | BCHEACHE | |
| SCHEMBL8810369 | 0.92 | DRD2 (0.56) | BCHEACHEDRD2DRD3 | |
| SCHEMBL8807935 | 0.91 | ACHE (0.60) | BCHEACHE | |
| SCHEMBL8809392 | 0.90 | DRD2 (0.56) | BCHEACHEKDM4EALDH1A1DRD2 | |
| SCHEMBL8809835 | 0.89 | BCHE (0.54) | BCHEACHEDRD2DRD3 | |
| SCHEMBL8808125 | 0.89 | HTR1A (0.56) | — | |
| SCHEMBL8809090 | 0.89 | BCHE (0.54) | BCHEACHEDRD2DRD3 | |
| SCHEMBL8807067 | 0.87 | ACHE (0.53) | BCHEACHEKDM4EALDH1A1DRD2 | |
| SCHEMBL8810740 | 0.86 | DRD2 (0.59) | DRD2 | |
| SCHEMBL15803181 | 0.85 | BCHE (0.70) | BCHEACHEKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584091-B1 | BENZOPYRANONES, METHODS OF MANUFACTURE AND USE THEREOF | SCHWABE WILLMAR GMBH & CO (DE) | 1997-01-15 | — | — | EP | disclosed |
| US-5428038-A | Administering for preventing or treating N-methyl-D-aspartate induced convulsions | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1995-06-27 | — | — | US | disclosed |
| EP-0584091-A1 | BENZOPYRANONES, METHODS OF MANUFACTURE AND USE THEREOF. | SCHWABE WILLMAR GMBH & CO (DE) | 1994-03-02 | — | — | EP | disclosed |
| WO-1992018493-A1 | BENZOPYRANONES, METHODS OF MANUFACTURE AND USE THEREOF | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1992-10-29 | — | — | WO | disclosed |