Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.60 |
| ▸ | BCHE | P06276 | 2/20 | 0.60 |
| ▸ | HTR1A | P08908 | 3/20 | 0.57 |
| ▸ | HTR2A | P28223 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810369 | 0.92 | DRD2 (0.56) | ACHEBCHEHTR1A | |
| SCHEMBL8807359 | 0.91 | BCHE (0.55) | ACHEBCHE | |
| SCHEMBL8809392 | 0.90 | DRD2 (0.56) | ACHEBCHEHTR1A | |
| SCHEMBL8809835 | 0.90 | BCHE (0.54) | ACHEBCHE | |
| SCHEMBL8809090 | 0.89 | BCHE (0.54) | ACHEBCHE | |
| SCHEMBL8807067 | 0.88 | ACHE (0.53) | ACHEBCHE | |
| SCHEMBL8807544 | 0.87 | BCHE (0.48) | ACHEBCHE | |
| SCHEMBL8810740 | 0.86 | DRD2 (0.59) | HTR2A | |
| SCHEMBL8806545 | 0.85 | DRD2 (0.51) | ACHEBCHEHTR2A | |
| SCHEMBL8806534 | 0.85 | ALDH1A1 (0.55) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584091-B1 | BENZOPYRANONES, METHODS OF MANUFACTURE AND USE THEREOF | SCHWABE WILLMAR GMBH & CO (DE) | 1997-01-15 | — | — | EP | disclosed |
| US-5428038-A | Administering for preventing or treating N-methyl-D-aspartate induced convulsions | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1995-06-27 | — | — | US | disclosed |
| EP-0584091-A1 | BENZOPYRANONES, METHODS OF MANUFACTURE AND USE THEREOF. | SCHWABE WILLMAR GMBH & CO (DE) | 1994-03-02 | — | — | EP | disclosed |
| WO-1992018493-A1 | BENZOPYRANONES, METHODS OF MANUFACTURE AND USE THEREOF | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1992-10-29 | — | — | WO | disclosed |