Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | GSK3A | P49840 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026440 | 0.89 | CA12 (0.50) | HTR2BMAOACA12CA1CA2 | |
| SCHEMBL968257 | 0.79 | MAPT (0.47) | MAPTSMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL11322723 | 0.77 | CTRC (0.49) | CA12CA1CA2CA3CA4 | |
| SCHEMBL11847254 | 0.76 | MAPT (0.72) | HTR2BCA1CA9MAPTSMN1; SMN2 | |
| SCHEMBL28836090 | 0.73 | HTR2B (0.54) | HTR2BCA12CA1CA2CA3 | |
| SCHEMBL15522925 | 0.73 | TDP1 (0.56) | FAAHMAPTRXFP1MAPK1HDAC3 | |
| Viridepyronone SCHEMBL18270619 | 0.73 | ALDH1A1 (0.40) | CA12CA9MAPTMAPK1HDAC3 | |
| SCHEMBL8116893 | 0.73 | HTR2B (0.56) | HTR2BMAPTSMN1; SMN2 | |
| SCHEMBL451456 | 0.72 | MAOA (0.74) | MAOAMAPTRXFP1MAOBSIGMAR1 | |
| SCHEMBL15577589 | 0.71 | SIGMAR1 (0.43) | MAOAFAAHMGLLMAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758327-A1 | PYRANONE COMPOUNDS USEFUL TO TREAT RETROVIRAL INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1997-02-19 | — | — | EP | claimed |