Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807862 | 0.98 | ABCG2 (0.43) | ABCG2ABCB1MAPTMEN1KMT2A | |
| SCHEMBL8808214 | 0.91 | ABCG2 (0.46) | ABCG2ABCB1MAPTNR1H4ALDH1A1 | |
| SCHEMBL8807856 | 0.89 | ABCG2 (0.45) | ABCG2ABCB1MAPTNR1H4ALDH1A1 | |
| SCHEMBL8809001 | 0.89 | KDR (0.47) | ABCG2MAPTMEN1KMT2AHPGD | |
| SCHEMBL8808228 | 0.83 | ABCG2 (0.43) | ABCG2ABCB1MAPTMEN1KMT2A | |
| SCHEMBL8807874 | 0.82 | ABCG2 (0.43) | ABCG2ABCB1MAPTMEN1KMT2A | |
| SCHEMBL8808995 | 0.81 | MCHR1 (0.49) | ABCG2ABCB1MEN1KMT2ATP53 | |
| SCHEMBL8815856 | 0.81 | MEN1 (0.40) | ABCG2ABCB1MAPTMEN1KMT2A | |
| SCHEMBL8815851 | 0.78 | BCHE (0.43) | ABCG2ABCB1MAPTMEN1KMT2A | |
| SCHEMBL8810669 | 0.78 | ABCB1 (0.68) | ABCG2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649410-B1 | ANILIDE DERIVATIVES | GLAXO LAB SA (FR) | 1997-05-02 | — | — | EP | disclosed |