Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8815856 | 0.88 | MEN1 (0.40) | ABCG2MCHR1KDRABCB1KDM4E | |
| SCHEMBL8808214 | 0.83 | ABCG2 (0.46) | BCHEACHEABCG2MCHR1ABCB1 | |
| SCHEMBL8807856 | 0.82 | ABCG2 (0.45) | BCHEACHEABCG2MCHR1ABCB1 | |
| SCHEMBL8815867 | 0.81 | MEN1 (0.38) | ABCG2ABCB1KDM4EALDH1A1NR1H4 | |
| SCHEMBL8808995 | 0.81 | MCHR1 (0.49) | BCHEACHEABCG2MCHR1KDR | |
| SCHEMBL8788717 | 0.79 | ABCG2 (0.57) | BCHEACHEABCG2ABCB1MAPT | |
| SCHEMBL8808218 | 0.78 | ABCG2 (0.44) | ABCG2ABCB1KDM4EALDH1A1HPGD | |
| SCHEMBL8790357 | 0.78 | ABCG2 (0.54) | BCHEACHEABCG2MCHR1ABCB1 | |
| SCHEMBL8830849 | 0.78 | MCHR1 (0.42) | BCHEACHEABCG2MCHR1ABCB1 | |
| SCHEMBL8807862 | 0.77 | ABCG2 (0.43) | ABCG2ABCB1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649410-B1 | ANILIDE DERIVATIVES | GLAXO LAB SA (FR) | 1997-05-02 | — | — | EP | disclosed |