Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7454500 | 0.77 | ALDH1A1 (0.32) | KCNN4MAPK1 | |
| SCHEMBL8128106 | 0.73 | KMT2A (0.35) | MAPK1 | |
| SCHEMBL9182082 | 0.73 | TSHR (0.30) | — | |
| SCHEMBL3825569 | 0.73 | TSHR (0.30) | — | |
| SCHEMBL25398456 | 0.73 | ENPP2 (0.36) | KCNN4MAPK1 | |
| SCHEMBL11202722 | 0.70 | IDO1 (0.38) | — | |
| SCHEMBL8721023 | 0.70 | TDP1 (0.34) | — | |
| SCHEMBL8809433 | 0.69 | NR1H2 (0.36) | NR1H2NR1H3MAPK1 | |
| SCHEMBL9185329 | 0.69 | AKR1B1 (0.41) | — | |
| SCHEMBL9181769 | 0.69 | LMNA (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |