Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 11/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 11/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29972806 | 0.91 | TP53 (0.42) | USP2ALDH1A1LMNANPSR1PPARG | |
| SCHEMBL8807728 | 0.91 | TP53 (0.42) | USP2ALDH1A1LMNANPSR1PPARG | |
| SCHEMBL8809049 | 0.91 | TP53 (0.42) | USP2ALDH1A1LMNANPSR1PPARG | |
| SCHEMBL8808860 | 0.90 | USP2 (0.43) | USP2ALDH1A1LMNANPSR1TP53 | |
| SCHEMBL9056629 | 0.86 | KMT2A (0.38) | USP2ALDH1A1LMNANPSR1TP53 | |
| SCHEMBL9058046 | 0.86 | UBE2M (0.41) | USP2ALDH1A1LMNANPSR1KDM4E | |
| SCHEMBL8807796 | 0.86 | THRB (0.39) | USP2ALDH1A1LMNANPSR1PPARG | |
| SCHEMBL8344843 | 0.85 | KDM4E (0.42) | USP2ALDH1A1TP53KDM4EHPGD | |
| SCHEMBL8338160 | 0.85 | SLC6A2 (0.44) | USP2ALDH1A1LMNANPSR1KDM4E | |
| SCHEMBL8810429 | 0.85 | LPAR1 (0.44) | LPAR1LPAR5USP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |