Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | USP2 | O75604 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 4/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808860 | 0.92 | USP2 (0.43) | KMT2AALDH1A1USP2NPSR1LMNA | |
| SCHEMBL8809049 | 0.92 | TP53 (0.42) | KMT2AMEN1ALDH1A1USP2NPSR1 | |
| SCHEMBL9058046 | 0.92 | UBE2M (0.41) | KMT2AMEN1ALDH1A1USP2NPSR1 | |
| SCHEMBL8807728 | 0.92 | TP53 (0.42) | KMT2AMEN1ALDH1A1USP2NPSR1 | |
| SCHEMBL29972806 | 0.92 | TP53 (0.42) | KMT2AMEN1ALDH1A1USP2NPSR1 | |
| SCHEMBL8808662 | 0.91 | KMT2A (0.38) | KMT2AMEN1ALDH1A1USP2NPSR1 | |
| SCHEMBL9056568 | 0.89 | KMT2A (0.41) | KMT2AMEN1ALDH1A1USP2NPSR1 | |
| SCHEMBL8808573 | 0.86 | LPAR1 (0.41) | KMT2AMEN1ALDH1A1USP2NPSR1 | |
| SCHEMBL8344843 | 0.85 | KDM4E (0.42) | ALDH1A1USP2KDM4ECYP1A2CYP3A4 | |
| SCHEMBL8856425 | 0.85 | GCGR (0.37) | ALDH1A1USP2NPSR1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |