Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | BACE1 | P56817 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | FABP6 | P51161 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8816552 | 0.83 | SLC6A2 (0.41) | HRH3MEN1KMT2AHDAC1KDM4E | |
| SCHEMBL8808730 | 0.78 | HRH3 (0.67) | HRH3MEN1KMT2ARAB9ACXCR4 | |
| SCHEMBL24093171 | 0.77 | HRH3 (0.86) | HRH3MEN1KMT2ARAB9ACXCR4 | |
| SCHEMBL8809487 | 0.77 | HRH3 (0.86) | HRH3MEN1KMT2ARAB9ACXCR4 | |
| SCHEMBL29771432 | 0.77 | L3MBTL1 (0.41) | MEN1KMT2ARAB9A | |
| SCHEMBL16249332 | 0.75 | MEN1 (0.83) | HRH3MEN1KMT2ARAB9ACXCR4 | |
| SCHEMBL8814676 | 0.75 | L3MBTL1 (0.40) | ALDH1A1 | |
| SCHEMBL8813574 | 0.72 | AGTR1 (0.47) | HRH3MEN1KMT2ARAB9ACXCR4 | |
| SCHEMBL294763 | 0.71 | HRH3 (0.71) | HRH3MEN1KMT2ARAB9AHDAC1 | |
| SCHEMBL24574127 | 0.71 | HRH3 (0.71) | HRH3MEN1KMT2ARAB9AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |