Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808906 | 0.83 | HRH3 (0.55) | KMT2AKDM4EALDH1A1MEN1HDAC1 | |
| SCHEMBL9057181 | 0.76 | SLC6A2 (0.64) | SLC6A2SLC6A4SLC6A3KMT2AKDM4E | |
| SCHEMBL5872540 | 0.75 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3KMT2AKDM4E | |
| SCHEMBL5872547 | 0.69 | SLC6A2 (0.69) | SLC6A2SLC6A4SLC6A3KMT2AKDM4E | |
| SCHEMBL19078741 | 0.69 | GRM4 (0.41) | ALDH1A1 | |
| SCHEMBL8809135 | 0.67 | MAP4K4 (0.45) | KMT2AALDH1A1MEN1HRH3 | |
| SCHEMBL70574 | 0.67 | L3MBTL1 (0.44) | KMT2AALDH1A1MEN1TYRO3L3MBTL1 | |
| SCHEMBL29771432 | 0.67 | L3MBTL1 (0.41) | KMT2AMEN1AXLL3MBTL1 | |
| SCHEMBL17276686 | 0.67 | TRPA1 (0.43) | ALOX15 | |
| SCHEMBL20979197 | 0.66 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |