Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | OXTR | P30559 | 1/20 | 0.30 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8806815 | 0.89 | ACHE (0.34) | LTB4R2ACHEPKMAGTR1 | |
| SCHEMBL8484079 | 0.86 | LTB4R2 (0.40) | LTB4R2ACHEPKMMEN1KMT2A | |
| SCHEMBL8487085 | 0.84 | LTB4R2 (0.36) | LTB4R2ACHEPKMMEN1KMT2A | |
| SCHEMBL1911 | 0.84 | LTB4R2 (0.48) | LTB4R2ACHEAGTR1OXTRAVPR1A | |
| SCHEMBL8487248 | 0.83 | LTB4R2 (0.34) | LTB4R2ACHEPKMMEN1KMT2A | |
| SCHEMBL8910748 | 0.83 | AGTR1 (0.36) | LTB4R2PKMMEN1KMT2AAGTR1 | |
| SCHEMBL2366 | 0.83 | LTB4R2 (0.47) | LTB4R2ACHEAGTR1OXTRAVPR1A | |
| SCHEMBL8484799 | 0.83 | LTB4R2 (0.34) | LTB4R2ACHEPKMMEN1KMT2A | |
| SCHEMBL9079126 | 0.81 | S1PR1 (0.35) | ACHEMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8911110 | 0.77 | LTB4R2 (0.34) | LTB4R2PKMAGTR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620998-A | CARDIOVASCULAR DISORDERS; HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-04-15 | — | — | US | disclosed |