Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.33 |
| ▸ | RELA | Q04206 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14046222 | 0.81 | MAPK9 (0.41) | MAPK9MAPK10ALOX15NPC1RAB9A | |
| SCHEMBL8809274 | 0.80 | ALOX15 (0.30) | ALOX15 | |
| SCHEMBL21196913 | 0.74 | MAPK9 (0.47) | MAPK9MAPK10ALOX15RAB9ASMN1; SMN2 | |
| SCHEMBL3460400 | 0.72 | ALOX15 (0.53) | ALOX15NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8809643 | 0.72 | ALDH1A1 (0.41) | NPC1RAB9ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL8810687 | 0.71 | KDM4E (0.37) | NPC1RAB9AALDH1A1MAPTLMNA | |
| SCHEMBL8811606 | 0.71 | KDM4E (0.30) | ALDH1A1LMNAKDM4EMEN1CYP1A2 | |
| SCHEMBL8556217 | 0.66 | MAPK9 (0.41) | MAPK9MAPK10ALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL2998557 | 0.66 | ALOX15 (0.40) | MAPK9MAPK10ALOX15NPC1RAB9A | |
| SCHEMBL8811740 | 0.64 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1TSHRMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794185-A1 | BICYCLIC THIAZOLE COMPOUND | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-09-10 | — | — | EP | disclosed |