SCHEMBL8809274

SCHEMBL8809274

CC(C)c1cn2c(CCCl)csc2n1

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14046228 0.83 ALOX15 (0.32) ALOX15
SCHEMBL14027767 0.81 ALOX15 (0.31) ALOX15
SCHEMBL8809096 0.80 MAPK9 (0.39) ALOX15
SCHEMBL8808546 0.74 ALDH1A1 (0.37)
SCHEMBL13390894 0.74 ALOX15 (0.47) ALOX15
SCHEMBL798504 0.74 ADORA3 (0.32) ALOX15
SCHEMBL27361269 0.68 ALOX15 (0.33) ALOX15
SCHEMBL14046222 0.60 MAPK9 (0.41) ALOX15
SCHEMBL8809643 0.60 ALDH1A1 (0.41)
SCHEMBL13248346 0.58 TP53 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0794185-A1 BICYCLIC THIAZOLE COMPOUND MEIJI SEIKA KABUSHIKI KAISHA (JP) 1997-09-10 EP disclosed