Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809153 | 0.83 | HTT (0.64) | HTTLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8809110 | 0.72 | MEN1 (0.55) | HTTLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL7309093 | 0.70 | KDM4E (0.65) | HTTLMNAALDH1A1FEN1SMN1; SMN2 | |
| SCHEMBL8810033 | 0.69 | HTT (0.64) | HTTLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9410763 | 0.67 | KCNH2 (0.43) | HTTLMNAALDH1A1FEN1SMN1; SMN2 | |
| SCHEMBL9410646 | 0.64 | PGR (0.43) | LMNAALDH1A1FEN1SMN1; SMN2KDM4E | |
| SCHEMBL7998576 | 0.64 | MEN1 (0.42) | LMNAALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL7997245 | 0.63 | NPC1 (0.52) | HTTLMNAALDH1A1KDM4EMAPT | |
| SCHEMBL7302698 | 0.63 | HTR3A (0.52) | LMNAKDM4EKCNH2 | |
| SCHEMBL7303669 | 0.63 | HTR3A (0.70) | SMN1; SMN2KDM4EHPGDKCNH2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505058-B1 | Thienopyridine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO KK (JP) | 1997-05-21 | — | — | EP | claimed |