Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 4/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574070 | 0.84 | ALDH1A1 (0.51) | TDP1L3MBTL1ALDH1A1HDAC1HDAC8 | |
| SCHEMBL8567801 | 0.80 | KCNK3 (0.55) | ALDH1A1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL14452372 | 0.79 | L3MBTL1 (0.61) | GAATDP1L3MBTL1CNR1CNR2 | |
| SCHEMBL10604764 | 0.79 | CNR1 (0.66) | GAATDP1L3MBTL1ALDH1A1CNR1 | |
| SCHEMBL30020929 | 0.78 | L3MBTL1 (0.60) | GAATDP1L3MBTL1ALDH1A1CNR1 | |
| SCHEMBL7935161 | 0.78 | L3MBTL1 (0.60) | GAATDP1L3MBTL1ALDH1A1CNR1 | |
| SCHEMBL7764626 | 0.78 | L3MBTL1 (0.60) | GAATDP1L3MBTL1ALDH1A1CNR1 | |
| SCHEMBL8443118 | 0.78 | ALDH1A1 (0.58) | ALDH1A1CNR1CNR2HDAC1HDAC8 | |
| SCHEMBL8445099 | 0.78 | ALDH1A1 (0.58) | ALDH1A1CNR1CNR2HDAC1HDAC8 | |
| SCHEMBL8570812 | 0.78 | GRM4 (0.54) | ALDH1A1HDAC1HDAC8HDAC6NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997000872-A1 | 1,3,8-TRIAZA- AND 3,8-DIAZA-1-OXASPIRO(4,5)DECANE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 1997-01-09 | — | — | WO | disclosed |