Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 6/20 | 0.45 |
| ▸ | OTC | P00480 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14848986 | 0.83 | LAP3 (0.48) | OTCALOX15MEN1CYP1A2KMT2A | |
| SCHEMBL8811075 | 0.75 | FDPS (0.36) | FDPSANPEP | |
| Arginine SCHEMBL508142 | 0.75 | OTC (0.62) | OTCALOX15MEN1CYP1A2KMT2A | |
| Arginine SCHEMBL11738420 | 0.75 | OTC (0.62) | OTCALOX15MEN1CYP1A2KMT2A | |
| Arginine SCHEMBL11738414 | 0.75 | OTC (0.62) | OTCALOX15MEN1CYP1A2KMT2A | |
| Arginine SCHEMBL508141 | 0.75 | OTC (0.62) | OTCALOX15MEN1CYP1A2KMT2A | |
| SCHEMBL2992625 | 0.75 | OTC (0.37) | OTCALOX15MEN1CYP1A2KMT2A | |
| SCHEMBL2992620 | 0.75 | OTC (0.47) | OTCALOX15MEN1CYP1A2KMT2A | |
| SCHEMBL3091575 | 0.75 | OTC (0.37) | OTCALOX15MEN1CYP1A2KMT2A | |
| Arginine SCHEMBL21747429 | 0.74 | OTC (0.60) | OTC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546548-B1 | Guanidinyl alkyl-1,1-bis phosphonic acid derivatives, process for their preparation and their use | HOECHST AG (DE) | 1997-05-02 | — | — | EP | claimed |
| EP-0546548-A1 | Guanidinyl alkyl-1,1-bis phosphonic acid derivatives, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-16 | — | — | EP | claimed |
| JP-5271260-A | — | — | None | — | — | JP | disclosed |
| EP-0546548-B1 | Guanidinyl alkyl-1,1-bis phosphonic acid derivatives, process for their preparation and their use | HOECHST AG (DE) | 1997-05-02 | — | — | EP | disclosed |
| US-5294608-A | Compounds for treatment of osteoporosis and bone disorders | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-15 | — | — | US | disclosed |
| JP-H05271260-A | GUANIDINOALKYL-1,1-BISPHOSPHONIC ACID DERIVATIVES, ITS PRODUCTION AND THEIR USE | HOECHST AG | 1993-10-19 | — | — | JP | disclosed |
| EP-0546548-A1 | Guanidinyl alkyl-1,1-bis phosphonic acid derivatives, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-16 | — | — | EP | disclosed |