Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 9/20 | 0.36 |
| ▸ | ANPEP | P15144 | 5/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | LAP3 | P28838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759492 | 0.77 | FDPS (0.39) | FDPSANPEPMMP1MMP8LAP3 | |
| SCHEMBL8809332 | 0.75 | FDPS (0.45) | FDPSANPEP | |
| SCHEMBL11137845 | 0.73 | — | — | |
| SCHEMBL11699720 | 0.73 | FDPS (0.39) | FDPSANPEPMMP1MMP8 | |
| Guanidine SCHEMBL10908988 | 0.71 | ALDH1A1 (0.31) | — | |
| SCHEMBL17234304 | 0.70 | PGK1 (0.44) | ANPEP | |
| Phosphonic Acid SCHEMBL8809887 | 0.68 | — | — | |
| SCHEMBL25658171 | 0.67 | MEN1 (0.32) | — | |
| SCHEMBL8764339 | 0.67 | FDPS (0.44) | FDPSANPEP | |
| SCHEMBL23961069 | 0.65 | NOS3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546548-B1 | Guanidinyl alkyl-1,1-bis phosphonic acid derivatives, process for their preparation and their use | HOECHST AG (DE) | 1997-05-02 | — | — | EP | claimed |
| EP-0546548-A1 | Guanidinyl alkyl-1,1-bis phosphonic acid derivatives, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-16 | — | — | EP | claimed |
| EP-0546548-B1 | Guanidinyl alkyl-1,1-bis phosphonic acid derivatives, process for their preparation and their use | HOECHST AG (DE) | 1997-05-02 | — | — | EP | disclosed |
| US-5294608-A | Compounds for treatment of osteoporosis and bone disorders | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-15 | — | — | US | disclosed |
| EP-0546548-A1 | Guanidinyl alkyl-1,1-bis phosphonic acid derivatives, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-16 | — | — | EP | disclosed |