Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690007 | 0.88 | RECQL (0.54) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL9689730 | 0.88 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL9688014 | 0.88 | NPC1 (0.47) | ALDH1A1MEN1KMT2ALMNATSHR | |
| SCHEMBL9687992 | 0.86 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL9689107 | 0.86 | TDP1 (0.41) | ALDH1A1MEN1KMT2ATSHRL3MBTL1 | |
| SCHEMBL16726836 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL9687989 | 0.84 | ELANE (0.38) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL9689342 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAALOX12TSHR | |
| SCHEMBL9689319 | 0.81 | TSHR (0.43) | ALDH1A1KMT2AMAPTLMNATSHR | |
| SCHEMBL9689977 | 0.80 | TDP1 (0.36) | ALDH1A1MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119039298-A | Preparation method of (strych) -5-benzoyl-2, 3-dihydro-1H-pyridine-1-carboxylic acid | 北京云鹏鹏程医药科技有限公司 | 2024-11-29 | — | — | CN | claimed |
| CN-119039298-A | Preparation method of (strych) -5-benzoyl-2, 3-dihydro-1H-pyridine-1-carboxylic acid | 北京云鹏鹏程医药科技有限公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-113185443-A | Preparation method of ketorolac tromethamine intermediate | 鲁南制药集团股份有限公司 | 2021-07-30 | — | — | CN | disclosed |
| EP-0486807-A1 | Process for preparing 5-aroyl-2,3-dihydro-1H-pyrrolizine-1,1-dicarboxylates | SYNTEX (U.S.A.) INC. (US) | 1992-05-27 | — | — | EP | disclosed |
| US-5082951-A | Process for preparing 5-aroyl-2,3-dihydro-1H-pyrrolizine-1,1-dicarboxylates (I) and intermediates therefor | SYNTEX (U.S.A.) INC. (US) | 1992-01-21 | — | — | US | disclosed |