Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 9/20 | 0.36 |
| ▸ | HTR1D | P28221 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 4/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | HTR1B | P28222 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | DRD5 | P21918 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809492 | 0.86 | DRD2 (0.40) | DRD2SLC6A4CTSSHTR2AHTR1D | |
| SCHEMBL8809322 | 0.86 | DRD2 (0.41) | DRD2SLC6A4CTSSHTR2AHTR1D | |
| SCHEMBL8810382 | 0.81 | DRD2 (0.57) | DRD2SLC6A4HTR2AHTR1DHTR1A | |
| SCHEMBL8810833 | 0.78 | DRD2 (0.43) | DRD2SLC6A4CTSSHTR2AHTR1D | |
| SCHEMBL8810281 | 0.77 | DYRK1A (0.41) | DRD2SLC6A4CTSSHTR2AHTR1D | |
| SCHEMBL8812864 | 0.73 | HTR1D (0.45) | DRD2SLC6A4HTR2AHTR1DHTR1A | |
| SCHEMBL8810725 | 0.73 | DRD2 (0.39) | DRD2SLC6A4CTSSHTR2AHTR1D | |
| SCHEMBL8917783 | 0.72 | CTSS (0.50) | DRD2SLC6A4CTSSHTR1DHTR1B | |
| SCHEMBL8810867 | 0.70 | DRD2 (0.58) | DRD2SLC6A4HTR2AHTR1DHTR1A | |
| SCHEMBL8809254 | 0.69 | DRD2 (0.57) | DRD2SLC6A4HTR2AHTR1DHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794185-A1 | BICYCLIC THIAZOLE COMPOUND | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-09-10 | — | — | EP | claimed |
| EP-0794185-A1 | BICYCLIC THIAZOLE COMPOUND | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-09-10 | — | — | EP | disclosed |