Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 5/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | OGA | O60502 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810833 | 0.83 | DRD2 (0.43) | CTSSDRD2SLC6A4HTR1DHTR1B | |
| SCHEMBL8808749 | 0.81 | HTR2A (0.60) | DRD2SLC6A4HTR1DHTR1BHTR2A | |
| SCHEMBL8809322 | 0.78 | DRD2 (0.41) | CTSSDRD2SLC6A4HTR1DHTR1B | |
| SCHEMBL8809441 | 0.77 | DRD2 (0.39) | CTSSDRD2SLC6A4HTR1DHTR1B | |
| SCHEMBL8917783 | 0.75 | CTSS (0.50) | CTSSDRD2SLC6A4HTR1DHTR1B | |
| SCHEMBL8809492 | 0.73 | DRD2 (0.40) | CTSSDRD2SLC6A4HTR1DHTR1B | |
| SCHEMBL8915757 | 0.72 | CTSS (0.51) | CTSSDRD2SLC6A4HTR1DHTR1B | |
| SCHEMBL8916709 | 0.72 | CTSS (0.49) | CTSSDRD2SLC6A4HTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL8920486 | 0.71 | CTSS (0.48) | CTSSDRD2SLC6A4HTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL6897558 | 0.71 | DRD2 (0.58) | DRD2HTR2AHTR1AADRA2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794185-A1 | BICYCLIC THIAZOLE COMPOUND | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-09-10 | — | — | EP | disclosed |