Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPM1 | P06748 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8812051 | 0.89 | HTT (0.52) | ALDH1A1LMNAFFAR1PPARGHTT | |
| SCHEMBL8809294 | 0.89 | FFAR1 (0.43) | ALDH1A1FFAR1PPARGPPARAL3MBTL1 | |
| SCHEMBL8685509 | 0.86 | POLB (0.50) | ALDH1A1LMNAFFAR1PPARGKMT2A | |
| SCHEMBL8811116 | 0.85 | ALDH1A1 (0.51) | ALDH1A1LMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL8812653 | 0.85 | ALDH1A1 (0.50) | ALDH1A1LMNAFFAR1PPARGSMN1; SMN2 | |
| SCHEMBL8811288 | 0.83 | CA2 (0.51) | FFAR1PPARGCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL8810885 | 0.83 | PARP1 (0.55) | ALDH1A1LMNAFFAR1PPARGCHRNB2 | |
| SCHEMBL8814248 | 0.82 | ALDH1A1 (0.42) | ALDH1A1LMNAFFAR1PPARGHTT | |
| SCHEMBL8810060 | 0.81 | MGAM (0.41) | ALDH1A1LMNAFFAR1PPARGHTT | |
| SCHEMBL8809489 | 0.81 | ALDH1A1 (0.41) | ALDH1A1LMNAHTTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | claimed |
| CN-1167111-A | Thiazolidinedione derivatives, method for preparing derivatives and pharmaceutical compositions containing same | SENGA PHARMACEUTICAL LAB INC (JP) | 1997-12-10 | — | — | CN | disclosed |
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |