Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | NPM1 | P06748 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8812059 | 0.89 | CYP19A1 (0.50) | ALDH1A1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8809304 | 0.89 | L3MBTL1 (0.38) | L3MBTL1CYP19A1PIK3CACHRM3PIK3R1 | |
| SCHEMBL8685513 | 0.86 | CYP19A1 (0.47) | ALDH1A1MEN1KMT2ALMNACYP19A1 | |
| SCHEMBL8812658 | 0.85 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2TDP1LMNACYP19A1 | |
| SCHEMBL8811123 | 0.85 | ALDH1A1 (0.51) | ALDH1A1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8811297 | 0.83 | MAPT (0.48) | ALDH1A1KMT2AL3MBTL1LMNAMAPT | |
| SCHEMBL8810896 | 0.83 | PARP1 (0.55) | ALDH1A1SMN1; SMN2LMNAMAPTPARP1 | |
| SCHEMBL8814259 | 0.81 | TNF (0.41) | ALDH1A1HTTSMN1; SMN2TDP1LMNA | |
| SCHEMBL8810072 | 0.81 | PARP1 (0.41) | ALDH1A1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8809479 | 0.81 | ALDH1A1 (0.41) | ALDH1A1HTTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | claimed |
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |