Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ICMT | O60725 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8685509 | 0.88 | POLB (0.50) | ALDH1A1LMNANPSR1CHRNB2CHRNA7 | |
| SCHEMBL8811861 | 0.88 | MAOA (0.47) | ALDH1A1LMNANPSR1MAPTMAOA | |
| SCHEMBL8811116 | 0.88 | ALDH1A1 (0.51) | ALDH1A1LMNANPSR1CHRNB2CHRNA7 | |
| SCHEMBL8811288 | 0.87 | CA2 (0.51) | MAPTCHRNB2CHRNA7CHRNA4POLB | |
| SCHEMBL8810885 | 0.85 | PARP1 (0.55) | ALDH1A1LMNAMAPTCHRNB2CHRNA7 | |
| SCHEMBL8809479 | 0.85 | ALDH1A1 (0.41) | ALDH1A1LMNANPSR1MAPTCHRNB2 | |
| SCHEMBL8814248 | 0.84 | ALDH1A1 (0.42) | ALDH1A1LMNANPSR1MAPTPARP1 | |
| SCHEMBL8810060 | 0.83 | MGAM (0.41) | ALDH1A1LMNANPSR1MAPTMAOA | |
| SCHEMBL8810491 | 0.83 | PPARG (0.51) | ALDH1A1LMNANPSR1MAPTFFAR1 | |
| SCHEMBL8811662 | 0.83 | CHRNB2 (0.52) | ALDH1A1NPSR1MAPTCHRNB2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167111-A | Thiazolidinedione derivatives, method for preparing derivatives and pharmaceutical compositions containing same | SENGA PHARMACEUTICAL LAB INC (JP) | 1997-12-10 | — | — | CN | disclosed |
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |