Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1848808 | 0.84 | SMO (0.46) | PTPN11MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1845477 | 0.81 | ALDH1A1 (0.49) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL1846364 | 0.81 | LMNA (0.42) | PTPN11MAPTTP53KMT2AALDH1A1 | |
| SCHEMBL1844792 | 0.78 | POLB (0.43) | MAPTKMT2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL4293606 | 0.76 | SMO (0.39) | MAPTMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL1848137 | 0.75 | KDM4E (0.51) | KMT2AALDH1A1TSHRKDM4E | |
| SCHEMBL1847339 | 0.75 | ALDH1A1 (0.48) | TP53MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL1848688 | 0.75 | ALDH1A1 (0.37) | PTPN11MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4837778 | 0.74 | HSP90AA1 (0.33) | MAPTMEN1KMT2AALDH1A1TSHR | |
| Maleic Acid SCHEMBL2882692 | 0.74 | POLB (0.42) | PTPN11MAPTKMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257102-B1 | AGENTS FOR TREATING NEUROPHATHY | MITSUI PETROCHEMICAL IND (JP) | 1997-11-19 | — | — | EP | disclosed |
| EP-0799617-A2 | Therapeutic agent for neurological diseases | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-08 | — | — | EP | disclosed |
| EP-0257102-A1 | AGENTS FOR TREATING NEUROPHATHY | Mitsui Chemicals, Inc. (JP) | 1988-03-02 | — | — | EP | disclosed |