Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ADCYAP1R1 | P41586 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ICMT | O60725 | 5/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810637 | 0.93 | PPARG (0.43) | PARP1FFAR1PPARGMAPTADCYAP1R1 | |
| SCHEMBL8813433 | 0.90 | PPARG (0.52) | FFAR1PPARGMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8810885 | 0.89 | PARP1 (0.55) | PARP1FFAR1PPARGMAPTLMNA | |
| SCHEMBL8810651 | 0.87 | MPO (0.46) | FFAR1PPARGLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8808968 | 0.87 | PPARG (0.41) | PARP1FFAR1PPARGMAPTLMNA | |
| SCHEMBL8685830 | 0.86 | PPARG (0.47) | FFAR1PPARGMAPTALDH1A1 | |
| SCHEMBL8811861 | 0.85 | MAOA (0.47) | FFAR1PPARGMAPTLMNATP53 | |
| SCHEMBL8810925 | 0.85 | PPARG (0.43) | FFAR1PPARGMAPTALDH1A1 | |
| SCHEMBL8809446 | 0.84 | PPARG (0.42) | FFAR1PPARGMAPTALDH1A1 | |
| SCHEMBL8811079 | 0.83 | KDM1A (0.42) | FFAR1PPARGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | claimed |
| CN-1167111-A | Thiazolidinedione derivatives, method for preparing derivatives and pharmaceutical compositions containing same | SENGA PHARMACEUTICAL LAB INC (JP) | 1997-12-10 | — | — | CN | disclosed |
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |