Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807990 | 0.75 | ACHE (0.37) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL11542708 | 0.69 | ALDH1A1 (0.59) | MAPK1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4496746 | 0.67 | PBRM1 (0.39) | NPSR1MAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9137877 | 0.67 | NPSR1 (0.43) | NPSR1ALDH1A1SMN1; SMN2 | |
| Pyrithiobac SCHEMBL23421324 | 0.65 | — | — | |
| SCHEMBL9142480 | 0.65 | CYP1A2 (0.41) | NPSR1 | |
| SCHEMBL8812629 | 0.65 | HSP90AA1 (0.35) | NPSR1HSP90AA1HSP90AB1EGFRFGFR1 | |
| SCHEMBL9139039 | 0.64 | ALDH1A1 (0.50) | NPSR1HSP90AA1HSP90AB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8810852 | 0.64 | NPSR1 (0.36) | NPSR1HSP90AA1HSP90AB1LMNAEGFR | |
| SCHEMBL2114306 | 0.64 | ALOX5 (0.33) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461079-B1 | Substituted phthalides and heterocyclic phthalides | CIBA GEIGY AG (CH) | 1997-07-16 | — | — | EP | disclosed |
| US-5627138-A | HERBICIDES | SANDOZ LTD. (CH) | 1997-05-06 | — | — | US | disclosed |
| US-5627137-A | HERBICIDES | SANDOZ LTD. (CH) | 1997-05-06 | — | — | US | disclosed |
| US-5561101-A | HERBICIDES | SANDOZ LTD. (CH) | 1996-10-01 | — | — | US | disclosed |
| US-5506192-A | HERBICIDES | SANDOZ LTD. | 1996-04-09 | — | — | US | disclosed |
| EP-0461079-A2 | Substituted phthalides and heterocyclic phthalides | SANDOZ LTD. (CH) | 1991-12-11 | — | — | EP | disclosed |