Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10393914 | 0.87 | TSHR (0.46) | TSHRCYP3A4ALDH1A1TDP1RECQL | |
| SCHEMBL2314823 | 0.81 | TSHR (0.49) | TSHRCYP3A4ALDH1A1TDP1RECQL | |
| SCHEMBL11520845 | 0.80 | TSHR (0.47) | TSHRCYP3A4ALDH1A1TDP1RECQL | |
| SCHEMBL11579509 | 0.76 | ALDH1A1 (0.42) | TSHRCYP3A4ALDH1A1TDP1RECQL | |
| SCHEMBL938653 | 0.76 | TSHR (0.57) | TSHRCYP3A4ALDH1A1TDP1RECQL | |
| SCHEMBL11095255 | 0.75 | TSHR (0.52) | TSHRCYP3A4ALDH1A1TDP1RECQL | |
| SCHEMBL11802146 | 0.75 | TSHR (0.49) | TSHRCYP3A4ALDH1A1TDP1RECQL | |
| SCHEMBL3192233 | 0.75 | GAA (0.47) | TSHRALDH1A1GAANSD2PLCG1 | |
| SCHEMBL8752103 | 0.74 | ALDH1A1 (0.38) | TSHRCYP3A4ALDH1A1TDP1RECQL | |
| SCHEMBL27966646 | 0.74 | ALDH1A1 (0.54) | TSHRCYP3A4ALDH1A1TDP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349980-B1 | Process for preparing 2-amino-6-nitro-benzoic acid | PERKINELMER HEALTH SCI INC (US) | 2018-09-26 | — | — | EP | disclosed |
| EP-2441805-B1 | Black disazo dyes, their preparation and their use | REX TONE IND LTD (IN) | 2016-07-20 | — | — | EP | disclosed |
| US-8835677-B2 | Methods for producing aminonitrobenzoic acids | PERKINELMER HEALTH SCIENCES, INC. (US) | 2014-09-16 | — | — | US | disclosed |
| US-8834620-B2 | Black disazo dyes, their preparation and use | ILFORD IMAGING SWITZERLAND GMBH (CH) | 2014-09-16 | — | — | US | disclosed |
| US-20120090503-A1 | BLACK DISAZO DYES, THEIR PREPARATION AND USE | ILFORD IMAGING SWITZERLAND GMBH | 2012-04-19 | — | — | US | disclosed |
| EP-2441805-A1 | Black disazo dyes, their preparation and their use | ILFORD Imaging Switzerland GmbH (CH) | 2012-04-18 | — | — | EP | disclosed |
| EP-2349980-A2 | METHODS FOR PRODUCING AMINONITROBENZOIC ACIDS | PerkinElmer Health Sciences, Inc. (US) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010045352-A2 | METHODS FOR PRODUCING AMINONITROBENZOIC ACIDS | PERKINELMER HEALTH SCIENCES, INC. (US) | 2010-04-22 | — | — | WO | disclosed |
| US-20100094046-A1 | METHODS FOR PRODUCING AMINONITROBENZOIC ACIDS | REVVITY HEALTH SCIENCES, INC. | 2010-04-15 | — | — | US | disclosed |
| US-20080075686-A1 | Deodorizer and method for using the same | TOTO LTD. (JP) | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100094046-A1 | METHODS FOR PRODUCING AMINONITROBENZOIC ACIDS | AADAT, DDC, DAO | TSHR 3799/4885CYP3A4 432/4885ALDH1A1 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.