Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 12/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | PPIB | P23284 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933283 | 0.84 | ACACB (0.31) | ELANE | |
| SCHEMBL7049734 | 0.81 | NAMPT (0.37) | NAMPTF2F10PLGPLAT | |
| SCHEMBL8933142 | 0.77 | F2 (0.40) | F2F10PLGPLATPRSS1 | |
| SCHEMBL8781082 | 0.77 | F2 (0.43) | NAMPTF2F10PLGPLAT | |
| SCHEMBL7987041 | 0.73 | NAMPT (0.37) | NAMPTF2F10PLGPLAT | |
| SCHEMBL7048448 | 0.67 | CNR1 (0.32) | F2 | |
| SCHEMBL8725592 | 0.65 | F2 (0.33) | NAMPTF2F10PLGPLAT | |
| SCHEMBL18300541 | 0.65 | L3MBTL1 (0.46) | NAMPTHDAC1CYP3A4 | |
| Acetic Acid SCHEMBL6477043 | 0.64 | NPC1L1 (0.32) | F2 | |
| SCHEMBL7705663 | 0.63 | OPRM1 (0.32) | F2ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996025426-A9 | NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS | — | 1997-06-12 | — | — | WO | disclosed |
| WO-1996025426-A1 | NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1996-08-22 | — | — | WO | disclosed |