Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 11/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | ICMT | O60725 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8812004 | 0.86 | — | — | |
| SCHEMBL8685513 | 0.81 | CYP19A1 (0.47) | HDAC1LMNAMEN1POLBKMT2A | |
| SCHEMBL8813439 | 0.79 | HTR6 (0.50) | LMNAMEN1POLBKMT2A | |
| SCHEMBL8809908 | 0.79 | MAPT (0.40) | ADAM17 | |
| SCHEMBL8685510 | 0.79 | HTR6 (0.49) | HDAC3LMNAPOLB | |
| SCHEMBL8809547 | 0.78 | ICMT (0.41) | HDAC3HDAC1HDAC2NCOR2ICMT | |
| SCHEMBL8811311 | 0.78 | NPC1 (0.50) | LMNAMEN1KMT2ATSHR | |
| SCHEMBL8810496 | 0.78 | HTR6 (0.49) | LMNA | |
| SCHEMBL8811798 | 0.78 | TP53 (0.46) | LMNAMEN1POLBKMT2AUSP2 | |
| SCHEMBL8690487 | 0.77 | KMT2A (0.50) | MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |