Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 6/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8812001 | 0.85 | PPARG (0.41) | MAPTMAOACISD1PPARGFFAR1 | |
| SCHEMBL8685509 | 0.81 | POLB (0.50) | PPARGFFAR1PPARANPSR1ALDH1A1 | |
| SCHEMBL8813431 | 0.80 | MAPT (0.56) | MAPTPPARGFFAR1PPARANPSR1 | |
| SCHEMBL8811306 | 0.80 | RAB9A (0.51) | MAPTNPSR1ALDH1A1GAA | |
| SCHEMBL8685503 | 0.80 | HTR6 (0.49) | MAPTPPARGFFAR1CA2PPARA | |
| SCHEMBL8809537 | 0.79 | ICMT (0.41) | MAPTMAOACISD1PPARGFFAR1 | |
| SCHEMBL8809916 | 0.79 | HDAC3 (0.35) | ADAM17 | |
| SCHEMBL8811662 | 0.79 | CHRNB2 (0.52) | MAPTPPARGFFAR1PPARANPSR1 | |
| SCHEMBL8690476 | 0.79 | KMT2A (0.51) | MAPTPPARGFFAR1NPSR1 | |
| SCHEMBL8810491 | 0.79 | PPARG (0.51) | MAPTPPARGFFAR1KCNH2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |