Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.57 |
| ▸ | NOX1 | Q9Y5S8 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | SMPD3 | Q9NY59 | 3/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810289 | 0.83 | NOX1 (0.62) | NOX1MAPTTP53ALOX5MEN1 | |
| SCHEMBL5676205 | 0.81 | NOX1 (0.76) | MPONOX1MAPTTP53THRB | |
| SCHEMBL175592 | 0.79 | SMPD3 (0.75) | MPONOX1MAPTTP53THRB | |
| Hydrochloric Acid SCHEMBL9648176 | 0.78 | SMPD3 (0.73) | MPONOX1MAPTTP53THRB | |
| SCHEMBL9425683 | 0.76 | SMPD3 (0.82) | MPONOX1MAPTTP53THRB | |
| SCHEMBL10702951 | 0.76 | MAPT (0.61) | MPONOX1MAPTTP53SMPD3 | |
| SCHEMBL9425980 | 0.75 | SMPD3 (0.53) | MPONOX1MAPTTP53THRB | |
| SCHEMBL9186957 | 0.75 | MPO (0.56) | MPONOX1MAPTTP53THRB | |
| SCHEMBL12103550 | 0.75 | SMPD3 (0.61) | MPONOX1MAPTTP53THRB | |
| SCHEMBL8809099 | 0.75 | NOX1 (0.61) | NOX1MAPTTP53ALOX5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812830-A1 | Modulators of multi-drug resistances | ONTOGEN CORPORATION (US) | 1997-12-17 | — | — | EP | disclosed |