Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.54 |
| ▸ | GCGR | P47871 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | BRAF | P15056 | 2/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808307 | 0.88 | NOX1 (0.58) | NOX1ALOX5GCGRMAPTTP53 | |
| SCHEMBL8810289 | 0.82 | NOX1 (0.62) | NOX1ALOX5GCGRMAPTTP53 | |
| SCHEMBL6467424 | 0.78 | NOX1 (0.72) | NOX1ALOX5GCGRMAPTTP53 | |
| SCHEMBL6620986 | 0.77 | ABCB1 (0.56) | NOX1ALOX5GCGRMAPTTP53 | |
| SCHEMBL1071183 | 0.76 | NOX1 (1.00) | NOX1ALOX5GCGRMAPTTP53 | |
| SCHEMBL6619832 | 0.75 | NOX1 (0.60) | NOX1ALOX5GCGRMAPTTP53 | |
| SCHEMBL8032578 | 0.75 | NOX1 (0.76) | NOX1ALOX5GCGRMAPTTP53 | |
| SCHEMBL5622957 | 0.75 | ALOX5 (0.87) | NOX1ALOX5GCGRMAPTBRAF | |
| SCHEMBL6468252 | 0.75 | NOX1 (0.76) | NOX1ALOX5GCGRMAPTTP53 | |
| SCHEMBL8810519 | 0.75 | MPO (0.57) | NOX1ALOX5MAPTTP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812830-A1 | Modulators of multi-drug resistances | ONTOGEN CORPORATION (US) | 1997-12-17 | — | — | EP | disclosed |