Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8811306 | 0.89 | RAB9A (0.51) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL8810577 | 0.87 | PARP1 (0.51) | ALDH1A1SMN1; SMN2HTTLMNAMEN1 | |
| SCHEMBL8811116 | 0.87 | ALDH1A1 (0.51) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL8808808 | 0.87 | PPARG (0.39) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL8810060 | 0.86 | MGAM (0.41) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL8814248 | 0.85 | ALDH1A1 (0.42) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL8811789 | 0.83 | CA2 (0.49) | LMNAMEN1MAPTKMT2ACA2 | |
| SCHEMBL8685509 | 0.82 | POLB (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL8810491 | 0.82 | PPARG (0.51) | ALDH1A1HTTLMNAMAPTCYP19A1 | |
| SCHEMBL8808926 | 0.81 | KDM1A (0.48) | MGAMGAASIMGAM2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | claimed |
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |