Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | UNG | P13051 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | NAT1 | P18440 | 2/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | TTK | P33981 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808298 | 0.79 | AXL (0.45) | TRIM24TRIM33AXLUNGCDK8 | |
| SCHEMBL8810439 | 0.77 | BCHE (0.39) | ALDH1A1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL10272478 | 0.73 | AXL (0.41) | TRIM24TRIM33AXLCDK8BRD4 | |
| SCHEMBL8812099 | 0.72 | SMN1; SMN2 (0.39) | ALDH1A1KDM4EMEN1POLBKMT2A | |
| SCHEMBL31541999 | 0.70 | NPC1 (0.44) | AXLMAOBALDH1A1CYP2A6KDM4E | |
| SCHEMBL8809141 | 0.68 | PARP1 (0.43) | MAOAALDH1A1KDM4EMEN1POLB | |
| SCHEMBL31541998 | 0.68 | NPC1 (0.44) | AXLMAOBALDH1A1CYP2A6KDM4E | |
| SCHEMBL29414645 | 0.67 | TRIM24 (0.69) | TRIM24TRIM33AXLUNGCDK8 | |
| SCHEMBL97618 | 0.67 | TRIM24 (0.69) | TRIM24TRIM33AXLUNGCDK8 | |
| SCHEMBL27790305 | 0.67 | GP6 (0.39) | TRIM24TRIM33AXLALDH1A1TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |