Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8812099 | 0.93 | SMN1; SMN2 (0.39) | BCHEALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL8809141 | 0.82 | PARP1 (0.43) | ALDH1A1KDM4EMEN1KMT2APARP1 | |
| SCHEMBL8810148 | 0.79 | BCHE (0.42) | BCHEALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL8810661 | 0.77 | TRIM24 (0.40) | ALDH1A1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL8808211 | 0.71 | BCHE (0.42) | BCHEALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL22000113 | 0.69 | BCHE (0.55) | BCHEALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL8811307 | 0.69 | BCHE (0.45) | BCHEALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL14562884 | 0.65 | MEN1 (0.64) | BCHEALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL8809897 | 0.65 | BCHE (0.44) | BCHEALDH1A1METAP2HIF1ASLC2A4 | |
| SCHEMBL8807533 | 0.64 | CHEK1 (0.41) | BCHEALDH1A1KDM4EHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |