Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 16/20 | 0.66 |
| ▸ | BCHE | P06276 | 11/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.49 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.49 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.49 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.49 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.49 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | FABP1 | P07148 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6492556 | 0.80 | ACHE (1.00) | ACHEBCHEALDH1A1KDM4E | |
| SCHEMBL6491511 | 0.74 | BCHE (1.00) | ACHEBCHEALDH1A1TSHRHSD17B10 | |
| SCHEMBL8022641 | 0.73 | ACHE (0.81) | ACHEBCHEALDH1A1KDM4ELMNA | |
| SCHEMBL12043418 | 0.72 | ACHE (1.00) | ACHEBCHE | |
| SCHEMBL8005649 | 0.71 | ACHE (0.78) | ACHEBCHEALDH1A1KDM4E | |
| SCHEMBL9584109 | 0.69 | ACHE (0.58) | ACHEBCHEALDH1A1TSHRHSD17B10 | |
| SCHEMBL9583451 | 0.69 | ACHE (0.62) | ACHEBCHEALDH1A1KDM4ETHRB | |
| SCHEMBL9550534 | 0.68 | BCHE (0.65) | ACHEBCHEALDH1A1TSHRHSD17B10 | |
| SCHEMBL2067900 | 0.68 | DHODH (0.49) | ACHEBCHEALDH1A1TSHRHSD17B10 | |
| Tacrine SCHEMBL1650622 | 0.67 | ACHE (0.93) | ACHEBCHEALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996018611-A2 | BENZOPHENANTHROLINES AND RELATED FUSED ACRIDINES | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 1996-06-20 | — | — | WO | claimed |
| WO-1996018611-A3 | BENZOPHENANTHROLINES AND RELATED FUSED ACRIDINES | UNIV CARDIFF (GB) | 1997-02-13 | — | — | WO | disclosed |
| WO-1996018611-A2 | BENZOPHENANTHROLINES AND RELATED FUSED ACRIDINES | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 1996-06-20 | — | — | WO | disclosed |
| WO-1996018611-A2 | BENZOPHENANTHROLINES AND RELATED FUSED ACRIDINES | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 1996-06-20 | — | — | WO | disclosed |