Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 15/20 | 0.78 |
| ▸ | BCHE | P06276 | 6/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6492556 | 0.84 | ACHE (1.00) | ACHEBCHEKDM4EALDH1A1 | |
| SCHEMBL6491511 | 0.76 | BCHE (1.00) | ACHEBCHEKDM4EALDH1A1 | |
| SCHEMBL12043418 | 0.74 | ACHE (1.00) | ACHEBCHE | |
| SCHEMBL8015766 | 0.72 | ACHE (0.71) | ACHEBCHEKDM4EALDH1A1 | |
| SCHEMBL8810684 | 0.71 | ACHE (0.66) | ACHEBCHEKDM4EALDH1A1 | |
| SCHEMBL27360248 | 0.71 | SRD5A1 (0.44) | ACHEKDM4E | |
| SCHEMBL7795994 | 0.70 | ACHE (0.67) | ACHEBCHEKDM4EALDH1A1 | |
| SCHEMBL11057550 | 0.70 | ACHE (0.67) | ACHEBCHEKDM4EALDH1A1 | |
| SCHEMBL8022641 | 0.69 | ACHE (0.81) | ACHEBCHEKDM4EALDH1A1 | |
| SCHEMBL13885533 | 0.67 | ACHE (0.68) | ACHEBCHEKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130228-A | Polycyclic compounds | UNIVERSITY OF STRATHCLYDE (GB) | 2000-10-10 | — | — | US | disclosed |