Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 11/20 | 0.44 |
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809310 | 0.90 | FFAR1 (0.42) | FFAR1PPARGPLA2G4AMAPTCA2 | |
| SCHEMBL8811053 | 0.87 | FFAR1 (0.42) | FFAR1PPARGMAPTCA2PPARA | |
| SCHEMBL8810504 | 0.79 | FFAR1 (0.41) | FFAR1PPARGMAPTCA2PPARA | |
| SCHEMBL8685509 | 0.79 | POLB (0.50) | FFAR1PPARGPPARAALDH1A1 | |
| SCHEMBL8809731 | 0.77 | HTR6 (0.56) | — | |
| SCHEMBL8685503 | 0.77 | HTR6 (0.49) | FFAR1PPARGMAPTCA2PPARA | |
| SCHEMBL8812828 | 0.76 | FFAR1 (0.39) | FFAR1PPARGMAPTCA2PPARA | |
| SCHEMBL8810470 | 0.76 | PLA2G4A (0.40) | PLA2G4AMAPTALDH1A1RECQL | |
| SCHEMBL8690476 | 0.76 | KMT2A (0.51) | FFAR1PPARGMAPT | |
| SCHEMBL8809908 | 0.74 | MAPT (0.40) | FFAR1PPARGMAPTCA2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167111-A | Thiazolidinedione derivatives, method for preparing derivatives and pharmaceutical compositions containing same | SENGA PHARMACEUTICAL LAB INC (JP) | 1997-12-10 | — | — | CN | disclosed |
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |