Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809719 | 0.89 | SLC2A1 (0.43) | MAPTPOLBALDH1A1L3MBTL1TP53 | |
| SCHEMBL8812658 | 0.87 | ALDH1A1 (0.47) | MAPTCHRNB2CHRNA7CHRNA4POLB | |
| SCHEMBL8685513 | 0.86 | CYP19A1 (0.47) | MAPTCHRNB2CHRNA7CHRNA4POLB | |
| SCHEMBL8811123 | 0.85 | ALDH1A1 (0.51) | POLBALDH1A1L3MBTL1KMT2ALMNA | |
| SCHEMBL8810896 | 0.83 | PARP1 (0.55) | MAPTALDH1A1HTR6TP53LMNA | |
| SCHEMBL8809489 | 0.83 | ALDH1A1 (0.41) | MAPTCHRNB2CHRNA7CHRNA4ALDH1A1 | |
| SCHEMBL8811798 | 0.82 | TP53 (0.46) | MAPTCHRNB2CHRNA7CHRNA4POLB | |
| SCHEMBL8809651 | 0.82 | SLC2A1 (0.36) | MAPTCHRNB2CHRNA7CHRNA4ALDH1A1 | |
| SCHEMBL8814259 | 0.81 | TNF (0.41) | POLBALDH1A1HTR6LMNA | |
| SCHEMBL8810072 | 0.81 | PARP1 (0.41) | CHRNB2CHRNA7CHRNA4POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |