Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | LPO | P22079 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809719 | 0.93 | SLC2A1 (0.43) | SLC2A1MAPTLMNATP53MEN1 | |
| SCHEMBL8810917 | 0.91 | CHRNB2 (0.41) | MAPTLMNATP53CHRNB2CHRNA7 | |
| SCHEMBL8808821 | 0.87 | CHRNB2 (0.44) | MAPTLMNAKMT2ACHRNB2CHRNA7 | |
| SCHEMBL8809469 | 0.86 | EGFR (0.39) | MAPTLMNATP53MEN1KMT2A | |
| SCHEMBL8813914 | 0.86 | CA2 (0.40) | MAPTTP53HDAC3HDAC1HDAC6 | |
| SCHEMBL8809453 | 0.85 | MPO (0.38) | SLC2A1BRD4LMNAMPOALDH1A1 | |
| SCHEMBL8685833 | 0.84 | HTR6 (0.43) | LMNAKMT2AMPOCHRNB2CHRNA7 | |
| SCHEMBL8811856 | 0.84 | DBH (0.41) | MAPTLMNATP53MEN1KMT2A | |
| SCHEMBL8811872 | 0.84 | SLC2A1 (0.41) | SLC2A1MAPTLMNATP53MEN1 | |
| SCHEMBL8814121 | 0.84 | PARP1 (0.41) | TP53MEN1KMT2AMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |