Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 6/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8812276 | 0.83 | DCUN1D1 (0.43) | UBE2MDCUN1D1 | |
| SCHEMBL9066708 | 0.78 | PTGES (0.36) | PTGESKDM4EALDH1A1NPSR1TRPV1 | |
| SCHEMBL8810320 | 0.77 | PTGES (0.38) | PTGESEGFRERBB2KDM4EALDH1A1 | |
| SCHEMBL8812096 | 0.76 | ALDH1A1 (0.40) | SMN1; SMN2KDM4EALDH1A1NPSR1 | |
| SCHEMBL8811464 | 0.76 | PTGES (0.43) | PTGESEGFRERBB2KDM4EALDH1A1 | |
| SCHEMBL8807676 | 0.70 | PTGES (0.37) | PTGESEGFRERBB2KDM4EROCK2 | |
| SCHEMBL27623829 | 0.69 | MAOB (0.40) | SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8810782 | 0.69 | BCHE (0.37) | SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3946590 | 0.66 | SOAT1 (0.44) | SOAT1 | |
| SCHEMBL3949700 | 0.65 | SOAT1 (0.45) | SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |