SCHEMBL8813314

SCHEMBL8813314

CCCCCCCCCC(I)(C(=O)OCC)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.44
▸ KMT2A Q03164 2/20 0.44
▸ MAPT P10636 1/20 0.44
▸ ATM Q13315 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ PIN1 Q13526 1/20 0.43
▸ PPARG P37231 1/20 0.41
▸ PPARA Q07869 1/20 0.41
▸ TSHR P16473 3/20 0.41
▸ LMNA P02545 3/20 0.41
▸ ALDH1A1 P00352 2/20 0.41
▸ CYP3A4 P08684 3/20 0.39
▸ CYP1A2 P05177 2/20 0.39
▸ CYP2D6 P10635 2/20 0.39
▸ CYP2C9 P11712 2/20 0.39
▸ CYP2C19 P33261 2/20 0.39
▸ SCN1A P35498 2/20 0.39
▸ SCN2A Q99250 2/20 0.39
▸ SCN3A Q9NY46 2/20 0.39
▸ NFKB1 P19838 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19066561 0.84 MEN1 (0.48) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL5046411 0.83 GAA (0.43) ALDH1A1GAASCN5ASCN9A
SCHEMBL3409880 0.83 GAA (0.43) ALDH1A1GAASCN5ASCN9A
SCHEMBL4582562 0.82 SCN1A (0.53) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL11274953 0.78 PIN1 (0.44) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL6871664 0.76 MEN1 (0.59) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL27941514 0.76 PIN1 (0.47) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL28047418 0.76 SCN1A (0.56) MEN1KMT2AATMPIN1TSHR
SCHEMBL13946533 0.76 MAPT (0.47) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL8482340 0.75 SCN1A (0.51) MEN1KMT2AMAPTPIN1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025052207-A1 DEVICES TO BE IMPLANTED INTO THE HUMAN BODY AND METHOD FOR THEIR REALIZATION TECRES S.P.A. (IT) 2025-03-13 — — WO claimed
US-20230414836-A1 DEVICES TO BE IMPLANTED INTO THE HUMAN BODY TECRES S.P.A. (IT) 2023-12-28 — — US claimed
WO-2025052207-A1 DEVICES TO BE IMPLANTED INTO THE HUMAN BODY AND METHOD FOR THEIR REALIZATION TECRES S.P.A. (IT) 2025-03-13 — — WO disclosed
US-20230414836-A1 DEVICES TO BE IMPLANTED INTO THE HUMAN BODY TECRES S.P.A. (IT) 2023-12-28 — — US disclosed
EP-0800404-A2 ORAL GASTROINTESTINAL DIAGNOSTIC X-RAY CONTRAST AGENTS IN COMBINATION WITH PHARMACEUTICALLY ACCEPTABLE CLAYS AND SURFACTANTS NanoSystems L.L.C. (US) 1997-10-15 — — EP disclosed
US-5628981-A Formulations of oral gastrointestinal diagnostic x-ray contrast agents and oral gastrointestinal therapeutic agents NANO SYSTEMS L.L.C. (US) 1997-05-13 — — US disclosed
WO-1996020734-A2 ORAL GASTROINTESTINAL X-RAY CONTRAST AGENTS IN COMBINATION WITH PHARMACEUTICALLY ACCEPTABLE CLAYS AND SURFACTANTS NANOSYSTEMS, L.L.C. (US) 1996-07-11 — — WO disclosed
WO-1996020735-A2 ORAL GASTROINTESTINAL X-RAY CONTRAST AGENTS IN COMBINATION WITH SURFACTANTS NANOSYSTEMS L.L.C. (US) 1996-07-11 — — WO disclosed
US-5466440-A Radioopaque crystalline material, surfactant stabilizer, clay EASTMAN KODAK COMPANY (US) 1995-11-14 — — US disclosed
US-5019370-A Biodegradable, low biological toxicity radiographic contrast medium and method of x-ray imaging UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1991-05-28 — — US disclosed
US-4406878-A Iodinated contrast agent for radiography EASTMAN KODAK COMPANY (US) 1983-09-27 — — US disclosed
US-4125554-A Iodinated thiolcarbonates and method for use as radiographic contrast agents ALCON LABORATORIES, INC. (US) 1978-11-14 — — US disclosed
Send feedback