Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5046411 | 1.00 | GAA (0.43) | GAASCN5ASCN9ACES2CES1 | |
| SCHEMBL8813314 | 0.83 | MEN1 (0.44) | GAASCN5ASCN9AALDH1A1 | |
| SCHEMBL10869954 | 0.81 | ALDH1A1 (0.49) | GAASCN5ASCN9ACES2CES1 | |
| SCHEMBL11305185 | 0.81 | ALDH1A1 (0.49) | GAASCN5ASCN9ACES2CES1 | |
| SCHEMBL5385328 | 0.81 | ALDH1A1 (0.49) | GAASCN5ASCN9ACES2CES1 | |
| SCHEMBL28570454 | 0.81 | ALDH1A1 (0.49) | GAASCN5ASCN9ACES2CES1 | |
| SCHEMBL355604 | 0.81 | ALDH1A1 (0.49) | GAASCN5ASCN9ACES2CES1 | |
| SCHEMBL11288238 | 0.79 | GAA (0.45) | GAASCN5ASCN9ACES2CES1 | |
| SCHEMBL10357746 | 0.79 | SCN5A (0.55) | GAASCN5ASCN9ACES2CES1 | |
| SCHEMBL11291699 | 0.79 | GAA (0.45) | GAASCN5ASCN9ACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3741381-B1 | A PEPTIDE FOR USE FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | UNIV CORNELL (US) | 2024-04-24 | — | — | EP | disclosed |
| US-20230398172-A1 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | CORNELL UNIVERSITY (US) | 2023-12-14 | — | — | US | disclosed |
| US-11628198-B2 | Methods for prevention and treatment of acute renal injury | CORNELL UNIVERSITY (US) | 2023-04-18 | — | — | US | disclosed |
| CN-109414220-B | Tactile sensing device for lumbar puncture | 德克萨斯医疗中心 | 2021-12-14 | — | — | CN | disclosed |
| US-20210023161-A1 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | CORNELL UNIVERSITY (US) | 2021-01-28 | — | — | US | disclosed |
| EP-3741381-A1 | A PEPTIDE FOR USE FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | Cornell University (US) | 2020-11-25 | — | — | EP | disclosed |
| CN-111601566-A | Tactile sensing and needle guide device | 因图伊泰普医疗公司 | 2020-08-28 | — | — | CN | disclosed |
| EP-3243521-B1 | A PEPTIDE FOR USE FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | UNIV CORNELL (US) | 2020-05-27 | — | — | EP | disclosed |
| US-20180177840-A1 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | CORNELL UNIVERSITY | 2018-06-28 | — | — | US | disclosed |
| EP-3243521-A1 | A PEPTIDE FOR USE FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | Cornell University (US) | 2017-11-15 | — | — | EP | disclosed |
| US-8940696-B2 | Methods for prevention and treatment of acute renal injury | CORNELL UNIVERSITY (US) | 2015-01-27 | — | — | US | disclosed |
| US-8592373-B2 | Methods for prevention and treatment of acute renal injury | CORNELL UNIVERSITY (US) | 2013-11-26 | — | — | US | disclosed |
| US-20130017150-A1 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | CORNELL UNIVERSITY | 2013-01-17 | — | — | US | disclosed |
| EP-2262520-A2 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | Cornell University (US) | 2010-12-22 | — | — | EP | disclosed |
| US-20090221514-A1 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | CORNELL UNIVERSITY | 2009-09-03 | — | — | US | disclosed |
| WO-2009108695-A2 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | CORNELL UNIVERSITY (US) | 2009-09-03 | — | — | WO | disclosed |
| EP-1024815-B1 | PHARMACEUTICAL COMPOSITIONS FOR ORAL ADMINISTRATION OF MOLECULAR IODINE | SYMBOLLON CORP (US) | 2003-01-29 | — | — | EP | disclosed |
| EP-1024815-A1 | PHARMACEUTICAL COMPOSITIONS FOR ORAL ADMINISTRATION OF MOLECULAR IODINE | Symbollon Corporation (US) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999021567-A1 | PHARMACEUTICAL COMPOSITIONS FOR ORAL ADMINISTRATION OF MOLECULAR IODINE | SYMBOLLON CORPORATION (US) | 1999-05-06 | — | — | WO | disclosed |
| US-5885592-A | FEEDING MAMMAL IODINE SPECIES OXIDANT AND IODINE REDUCTANT CONTAINING IODINE SPECIES WHICH UNDERGOES OXIDATION-REDUCTION REACTION ON CONTACT WITH GASTRIC JUICE TO GENERATE MOLECULAR IODINE IN VIVO | SYMBOLLON CORPORATION (US) | 1999-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11628198-B2 | Methods for prevention and treatment of acute renal injury | ARG2, SERPINC1, ARG1 | GAA 2381/4885SCN5A 4479/4885SCN9A 3767/4885 |
| US-20230398172-A1 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | ARG2, SERPINC1, ARG1 | GAA 2381/4885SCN5A 4479/4885SCN9A 3767/4885 |
| US-20180177840-A1 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | ARG2, SERPINC1, ARG1 | GAA 2381/4885SCN5A 4479/4885SCN9A 3767/4885 |
| US-20130017150-A1 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | ARG2, SERPINC1, ARG1 | GAA 2381/4885SCN5A 4479/4885SCN9A 3767/4885 |
| US-20090221514-A1 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | ARG2, SERPINC1, ARG1 | GAA 2381/4885SCN5A 4479/4885SCN9A 3767/4885 |
| US-20210023161-A1 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | ARG2, SERPINC1, ARG1 | GAA 2381/4885SCN5A 4479/4885SCN9A 3767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.