Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28564255 | 0.89 | LMNA (0.42) | LMNAHTTCYP2D6MAPK1SMN1; SMN2 | |
| SCHEMBL9542136 | 0.81 | CA2 (0.36) | LMNAHTTSMN1; SMN2MAPTSNCA | |
| SCHEMBL16028576 | 0.80 | CYP1A2 (0.36) | LMNAHTTMAPTSNCAS1PR3 | |
| SCHEMBL8971719 | 0.80 | CA2 (0.42) | LMNAHTTSMN1; SMN2MAPTSNCA | |
| SCHEMBL9099551 | 0.80 | HTT (0.47) | LMNAHTTCYP2D6MAPK1SMN1; SMN2 | |
| SCHEMBL9101573 | 0.79 | CYP2C19 (0.37) | LMNAHTTCYP2D6MAPTSNCA | |
| SCHEMBL9568601 | 0.78 | NR1I2 (0.35) | LMNAHTTSMN1; SMN2MAPTSNCA | |
| SCHEMBL9277018 | 0.76 | LMNA (0.47) | LMNAHTTCYP2D6MAPK1SMN1; SMN2 | |
| SCHEMBL8586535 | 0.76 | HTT (0.39) | HTTSMN1; SMN2TSHRNPSR1SNCA | |
| SCHEMBL9098604 | 0.76 | SMN1; SMN2 (0.39) | CYP2D6MAPK1SMN1; SMN2TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997023458-A1 | SUBTYPE-SELECTIVE NMDA RECEPTOR LIGANDS AND THE USE THEREOF | WARNER-LAMBERT COMPANY (US) | 1997-07-03 | — | — | WO | disclosed |