SCHEMBL9101573

SCHEMBL9101573

CCCC(c1cc(S(=O)(=O)O)ccc1C)c1cc(C)ccc1S(=O)(=O)O

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 3/20 0.37
CYP2C9 P11712 2/20 0.37
TP53 P04637 1/20 0.37
CYP2D6 P10635 1/20 0.37
ALOX15 P16050 1/20 0.37
ALDH1A1 P00352 6/20 0.35
HIF1A Q16665 1/20 0.35
CA12 O43570 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
SNCA P37840 1/20 0.35
LMNA P02545 2/20 0.33
MAPT P10636 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
S1PR3 Q99500 1/20 0.33
HTT P42858 1/20 0.33
RAPGEF4 Q8WZA2 1/20 0.32
CYP1A2 P05177 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8813449 0.79 LMNA (0.43) CYP2C19CYP2C9TP53CYP2D6ALOX15
SCHEMBL7248678 0.79 LMNA (0.47) CYP2D6ALDH1A1LMNAMAPTL3MBTL1
SCHEMBL9541772 0.77 CA12 (0.36) ALDH1A1HIF1ACA12CA2CA9
SCHEMBL9542136 0.77 CA2 (0.36) ALDH1A1CA12CA2CA9SNCA
SCHEMBL8971717 0.76 CA12 (0.42) CYP2C19ALDH1A1CA12CA2CA9
SCHEMBL8470868 0.76 PDE5A (0.44) CYP2C19ALDH1A1HIF1ACA12CA2
SCHEMBL10771314 0.76 CA12 (0.42) CYP2C19ALDH1A1CA12CA2CA9
SCHEMBL8971719 0.76 CA2 (0.42) ALDH1A1CA12CA2CA9SNCA
SCHEMBL16028576 0.76 CYP1A2 (0.36) CYP2C19ALDH1A1CA12CA2CA9
SCHEMBL9568601 0.74 NR1I2 (0.35) ALDH1A1CA12CA2CA9SNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5489501-A MIXTURES OF TWO COORDINATION COMPOUNDS WHICH REACT TO FORM NEW COORDINATION COMPOUND WHILE CAUSING VISIBLE COLOR CHANGES RICOH COMPANY, LTD. (JP) 1996-02-06 US disclosed
US-5446011-A Imagewise coloring when heating; mixture of n-substituted indole, aromatic polyhydroxy compound, carbonyl compound and an acid RICOH COMPANY, LTD. (JP) 1995-08-29 US disclosed