Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371628 | 0.91 | KCNMA1 (0.48) | KCNMA1KDM4EHIF1AF10SMN1; SMN2 | |
| SCHEMBL8812136 | 0.90 | SMN1; SMN2 (0.46) | KCNMA1KDM4ETP53GAAF10 | |
| SCHEMBL7372454 | 0.89 | KCNMA1 (0.48) | KCNMA1KDM4ETP53GAASMN1; SMN2 | |
| SCHEMBL8816300 | 0.88 | BRD4 (0.45) | KCNMA1KDM4ETP53GAAF10 | |
| SCHEMBL8814391 | 0.85 | POLB (0.46) | KCNMA1KDM4EHIF1ATP53GAA | |
| SCHEMBL7512858 | 0.85 | ALDH1A1 (0.50) | KCNMA1TP53GAASMN1; SMN2MAPT | |
| SCHEMBL8814423 | 0.84 | TP53 (0.45) | KDM4ETP53GAASMN1; SMN2MAPT | |
| SCHEMBL8812490 | 0.81 | TP53 (0.41) | TP53GAASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7748399 | 0.81 | ALDH1A1 (0.51) | KCNMA1TP53GAASMN1; SMN2MAPT | |
| SCHEMBL7375499 | 0.80 | MTTP (0.47) | KDM4EF10SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |