Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 4/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8816300 | 0.92 | BRD4 (0.45) | PTGER1BRD4HPGDKDM4EMEN1 | |
| SCHEMBL7376652 | 0.92 | PTGER1 (0.46) | MTTPPTGER1BRD4HPGDMAPT | |
| SCHEMBL7371809 | 0.92 | PTGER1 (0.46) | PTGER1BRD4HPGDKDM4EMAPT | |
| SCHEMBL7749370 | 0.89 | CYP19A1 (0.49) | PTGER1CYP19A1AVPR2 | |
| SCHEMBL7519200 | 0.88 | MTTP (0.42) | MTTPHPGDKDM4EF10ALDH1A1 | |
| SCHEMBL7371628 | 0.87 | KCNMA1 (0.48) | MTTPHPGDKDM4EMEN1ESR1 | |
| SCHEMBL7370837 | 0.87 | MTTP (0.48) | MTTPPTGER1POLBMAPTCYP19A1 | |
| SCHEMBL7369948 | 0.85 | MTTP (0.39) | MTTPHPGDKDM4EF10ALDH1A1 | |
| SCHEMBL8814366 | 0.85 | CYP19A1 (0.44) | PTGER1BRD4HPGDKDM4EMAPT | |
| SCHEMBL7512593 | 0.84 | CYP19A1 (0.45) | MTTPPTGER1HPGDMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |