Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 3/20 | 0.43 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373393 | 0.90 | ALDH1A1 (0.47) | SMN1; SMN2NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL8813752 | 0.90 | KCNMA1 (0.49) | SMN1; SMN2NPC1TP53ALDH1A1F10 | |
| SCHEMBL7513968 | 0.83 | RAB9A (0.46) | NPC1RAB9ATP53ALDH1A1F10 | |
| SCHEMBL8814928 | 0.83 | NPC1 (0.46) | SMN1; SMN2NPC1RAB9ATP53PPARG | |
| SCHEMBL8814391 | 0.80 | POLB (0.46) | SMN1; SMN2NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL7371628 | 0.80 | KCNMA1 (0.48) | SMN1; SMN2NPC1RAB9AALDH1A1F10 | |
| SCHEMBL8814366 | 0.79 | CYP19A1 (0.44) | SMN1; SMN2NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL7376165 | 0.78 | AVPR2 (0.48) | SMN1; SMN2NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL8816300 | 0.78 | BRD4 (0.45) | SMN1; SMN2NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL8812151 | 0.78 | GAA (0.41) | SMN1; SMN2TP53ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |